/* ============================================================
   APOGEE — Clinical report visuals
   Sample biomarker panels, risk synthesis cards, trajectory.
   All values are SAMPLE data; this is illustrative UI, not a clinical product.
   ============================================================ */

/* ---------- Sample report frame ---------- */
.report {
  background: var(--color-surface);
  border: 1px solid var(--color-border);
  border-radius: var(--radius-lg);
  overflow: hidden;
  box-shadow: var(--shadow-lg);
  display: flex;
  flex-direction: column;
}
.report-head {
  display: flex;
  justify-content: space-between;
  gap: var(--space-4);
  padding: var(--space-5) var(--space-6);
  border-bottom: 1px solid var(--color-divider);
  background: var(--color-surface-2);
  font-family: var(--font-mono);
  font-size: 11px;
  letter-spacing: 0.1em;
  text-transform: uppercase;
  color: var(--color-text-muted);
}
.report-head .left { display: flex; gap: var(--space-4); align-items: center; }
.report-head .dot {
  width: 8px; height: 8px; border-radius: 999px;
  background: var(--color-primary);
  box-shadow: 0 0 0 4px var(--color-primary-soft);
}
.report-body { padding: var(--space-6); display: grid; gap: var(--space-6); }

/* ---------- Patient/Subject header ---------- */
.subj-head {
  display: grid;
  grid-template-columns: 1fr auto;
  gap: var(--space-4);
  align-items: end;
  padding-bottom: var(--space-5);
  border-bottom: 1px solid var(--color-divider);
}
.subj-name {
  font-family: var(--font-display);
  font-size: var(--text-lg);
  font-weight: 500;
  letter-spacing: -0.01em;
  color: var(--color-text-strong);
}
.subj-meta {
  font-family: var(--font-mono);
  font-size: 11px;
  letter-spacing: 0.08em;
  color: var(--color-text-faint);
  text-transform: uppercase;
  margin-top: 4px;
}
.subj-id {
  font-family: var(--font-mono);
  font-size: 11px;
  color: var(--color-text-muted);
  letter-spacing: 0.06em;
}

/* ---------- Risk synthesis (large readout) ---------- */
.risk-synth {
  display: grid;
  grid-template-columns: 160px 1fr;
  gap: var(--space-6);
  align-items: center;
}
@media (max-width: 540px) {
  .risk-synth { grid-template-columns: 1fr; }
}

.risk-gauge {
  position: relative;
  width: 160px; height: 160px;
}
.risk-gauge svg { width: 100%; height: 100%; }
.risk-gauge .gauge-center {
  position: absolute;
  inset: 0;
  display: flex;
  flex-direction: column;
  align-items: center;
  justify-content: center;
  gap: 2px;
  text-align: center;
}
.risk-gauge .gauge-num {
  font-family: var(--font-display);
  font-size: 36px;
  font-weight: 500;
  letter-spacing: -0.04em;
  color: var(--color-text-strong);
  line-height: 1;
}
.risk-gauge .gauge-lbl {
  font-family: var(--font-mono);
  font-size: 10px;
  letter-spacing: 0.16em;
  text-transform: uppercase;
  color: var(--color-text-faint);
}

.risk-details { display: flex; flex-direction: column; gap: var(--space-3); }
.risk-headline {
  display: flex; align-items: center; gap: var(--space-3); flex-wrap: wrap;
}
.risk-headline h4 {
  font-family: var(--font-display);
  font-size: var(--text-base);
  letter-spacing: -0.01em;
  font-weight: 500;
  color: var(--color-text-strong);
  margin: 0;
}
.risk-meta {
  font-family: var(--font-body);
  font-size: var(--text-sm);
  color: var(--color-text-muted);
  line-height: 1.55;
}

/* ---------- Biomarker panel ---------- */
.biomarker-panel {
  display: grid;
  grid-template-columns: repeat(2, 1fr);
  gap: var(--space-3);
}
@media (max-width: 540px) {
  .biomarker-panel { grid-template-columns: 1fr; }
}
.biomarker {
  display: grid;
  grid-template-columns: 1fr auto;
  gap: var(--space-3);
  padding: var(--space-4);
  background: var(--color-surface-2);
  border: 1px solid var(--color-divider);
  border-radius: var(--radius-md);
}
.biomarker .name {
  font-family: var(--font-body);
  font-size: 13px;
  color: var(--color-text-strong);
  font-weight: 500;
  letter-spacing: -0.005em;
}
.biomarker .ref {
  font-family: var(--font-mono);
  font-size: 10px;
  color: var(--color-text-faint);
  letter-spacing: 0.06em;
  margin-top: 2px;
}
.biomarker .val {
  text-align: right;
}
.biomarker .val .v {
  font-family: var(--font-display);
  font-size: 18px;
  font-weight: 500;
  letter-spacing: -0.02em;
  font-variant-numeric: tabular-nums;
  color: var(--color-text-strong);
  display: block;
}
.biomarker .val .u {
  font-family: var(--font-mono);
  font-size: 10px;
  color: var(--color-text-faint);
  letter-spacing: 0.05em;
}
.biomarker .flag {
  display: inline-block;
  margin-top: 4px;
  padding: 2px 6px;
  font-family: var(--font-mono);
  font-size: 9px;
  letter-spacing: 0.12em;
  text-transform: uppercase;
  border-radius: 4px;
}
.flag-elev { background: rgba(217,112,112,0.14); color: var(--color-danger); }
.flag-watch { background: rgba(212,168,87,0.16); color: var(--color-gold); }
.flag-opt { background: rgba(111,191,123,0.16); color: var(--color-success); }
.flag-bord { background: rgba(121,168,217,0.16); color: var(--color-info); }

/* Sparkline inline */
.biomarker.has-spark { grid-template-columns: 1fr auto auto; align-items: center; }
.biomarker .spark { width: 64px; height: 22px; color: var(--color-primary); }

/* ---------- Phenotype card ---------- */
.phenotype {
  display: grid;
  grid-template-columns: 1fr 1fr;
  gap: var(--space-5);
  padding: var(--space-5);
  background: linear-gradient(180deg, var(--color-surface-2), var(--color-surface));
  border: 1px solid var(--color-divider);
  border-radius: var(--radius-md);
}
@media (max-width: 540px) { .phenotype { grid-template-columns: 1fr; } }
.phenotype h5 {
  font-family: var(--font-mono);
  font-size: 10px;
  letter-spacing: 0.16em;
  text-transform: uppercase;
  color: var(--color-text-faint);
  font-weight: 500;
  margin-bottom: var(--space-2);
}
.phenotype .ptype {
  font-family: var(--font-display);
  font-size: 18px;
  letter-spacing: -0.01em;
  color: var(--color-text-strong);
  font-weight: 500;
  display: block;
  margin-bottom: var(--space-2);
}
.phenotype .ptags { display: flex; flex-wrap: wrap; gap: 6px; }

/* ---------- Trajectory card ---------- */
.trajectory {
  padding: var(--space-5);
  background: var(--color-surface-2);
  border: 1px solid var(--color-divider);
  border-radius: var(--radius-md);
}
.trajectory-head {
  display: flex;
  justify-content: space-between;
  align-items: center;
  margin-bottom: var(--space-3);
}
.trajectory-head h5 {
  font-family: var(--font-mono);
  font-size: 10px;
  letter-spacing: 0.16em;
  text-transform: uppercase;
  color: var(--color-text-faint);
  font-weight: 500;
}
.trajectory-head .delta {
  font-family: var(--font-mono);
  font-size: 11px;
  color: var(--color-success);
  letter-spacing: 0.04em;
}
.trajectory-chart { width: 100%; height: 100px; }
.trajectory-axis {
  display: flex; justify-content: space-between;
  margin-top: var(--space-2);
  font-family: var(--font-mono);
  font-size: 10px;
  color: var(--color-text-faint);
  letter-spacing: 0.08em;
}

/* ---------- Clinician recommendations ---------- */
.recs {
  display: flex; flex-direction: column;
  gap: 0;
  padding: var(--space-5);
  background: var(--color-surface-2);
  border: 1px solid var(--color-divider);
  border-radius: var(--radius-md);
}
.recs h5 {
  font-family: var(--font-mono);
  font-size: 10px;
  letter-spacing: 0.16em;
  text-transform: uppercase;
  color: var(--color-text-faint);
  font-weight: 500;
  margin-bottom: var(--space-3);
}
.rec {
  display: grid;
  grid-template-columns: auto 1fr auto;
  gap: var(--space-3);
  align-items: center;
  padding: var(--space-3) 0;
  border-bottom: 1px dashed var(--color-divider);
}
.rec:last-child { border-bottom: none; }
.rec .ix {
  width: 24px; height: 24px;
  border-radius: 4px;
  background: var(--color-primary-soft);
  color: var(--color-primary);
  display: inline-flex; align-items: center; justify-content: center;
  font-family: var(--font-mono);
  font-size: 10px;
  font-weight: 600;
}
.rec .body {
  font-family: var(--font-body);
  font-size: 13px;
  color: var(--color-text);
  line-height: 1.5;
}
.rec .pri {
  font-family: var(--font-mono);
  font-size: 9px;
  letter-spacing: 0.14em;
  text-transform: uppercase;
  color: var(--color-text-faint);
}

/* ---------- Mini dashboard tile ---------- */
.tile {
  background: var(--color-surface);
  border: 1px solid var(--color-border);
  border-radius: var(--radius-md);
  padding: var(--space-4);
}
.tile h6 {
  font-family: var(--font-mono);
  font-size: 10px;
  letter-spacing: 0.14em;
  text-transform: uppercase;
  color: var(--color-text-faint);
  font-weight: 500;
  margin-bottom: var(--space-2);
}
.tile .val {
  font-family: var(--font-display);
  font-size: 24px;
  font-weight: 500;
  letter-spacing: -0.025em;
  color: var(--color-text-strong);
}
.tile .sub {
  font-size: 12px;
  color: var(--color-text-muted);
  margin-top: 2px;
}

/* ---------- Workflow diagram ---------- */
.workflow {
  display: grid;
  grid-template-columns: repeat(5, 1fr);
  gap: 0;
  position: relative;
}
.workflow .node {
  position: relative;
  padding: var(--space-5);
  border: 1px solid var(--color-border);
  background: var(--color-surface);
  border-radius: var(--radius-md);
  display: flex;
  flex-direction: column;
  gap: var(--space-2);
  z-index: 1;
}
.workflow .node + .node { margin-left: -1px; border-radius: 0; }
.workflow .node:first-child { border-radius: var(--radius-md) 0 0 var(--radius-md); }
.workflow .node:last-child  { border-radius: 0 var(--radius-md) var(--radius-md) 0; }
.workflow .step {
  font-family: var(--font-mono);
  font-size: 10px;
  letter-spacing: 0.16em;
  color: var(--color-primary);
}
.workflow .lbl {
  font-family: var(--font-display);
  font-size: 14px;
  color: var(--color-text-strong);
  font-weight: 500;
  letter-spacing: -0.01em;
}
.workflow .meta {
  font-size: 12px;
  color: var(--color-text-muted);
  line-height: 1.5;
}
@media (max-width: 980px) {
  .workflow { grid-template-columns: repeat(2, 1fr); gap: var(--space-3); }
  .workflow .node { margin-left: 0 !important; border-radius: var(--radius-md) !important; }
}
@media (max-width: 480px) {
  .workflow { grid-template-columns: 1fr; }
}

/* ---------- Quote / Pull ---------- */
.pullquote {
  font-family: var(--font-display);
  font-size: var(--text-lg);
  font-weight: 500;
  line-height: 1.35;
  letter-spacing: -0.015em;
  color: var(--color-text-strong);
  border-left: 2px solid var(--color-primary);
  padding-left: var(--space-5);
  max-width: 60ch;
}

/* ---------- Two-col content blocks ---------- */
.split {
  display: grid;
  grid-template-columns: 1fr 1fr;
  gap: clamp(var(--space-8), 5vw, var(--space-16));
  align-items: start;
}
.split--alt { grid-template-columns: 1fr 1.1fr; }
@media (max-width: 900px) {
  .split,
  .split--alt { grid-template-columns: 1fr; }
}

/* ---------- List variants ---------- */
.spec-list { list-style: none; display: flex; flex-direction: column; }
.spec-list li {
  display: grid;
  grid-template-columns: 160px 1fr;
  gap: var(--space-5);
  padding: var(--space-4) 0;
  border-bottom: 1px solid var(--color-divider);
  font-size: var(--text-sm);
}
.spec-list li:last-child { border-bottom: none; }
.spec-list .k {
  font-family: var(--font-mono);
  font-size: 11px;
  letter-spacing: 0.14em;
  text-transform: uppercase;
  color: var(--color-text-faint);
  padding-top: 2px;
}
.spec-list .v { color: var(--color-text); line-height: 1.55; }
@media (max-width: 600px) {
  .spec-list li { grid-template-columns: 1fr; gap: var(--space-1); }
}

/* ---------- Compliance / disclaimer block ---------- */
.note {
  font-size: var(--text-xs);
  color: var(--color-text-faint);
  line-height: 1.5;
  letter-spacing: 0.01em;
  max-width: 80ch;
}
.note-block {
  margin-top: var(--space-12);
  padding: var(--space-5);
  border: 1px dashed var(--color-border);
  border-radius: var(--radius-md);
  background: color-mix(in oklab, var(--color-surface) 50%, transparent);
}

/* ---------- Big CTA band ---------- */
.cta-band {
  background: linear-gradient(180deg, var(--color-surface), var(--color-surface-2));
  border: 1px solid var(--color-border);
  border-radius: var(--radius-xl);
  padding: clamp(var(--space-10), 5vw, var(--space-16));
  display: grid;
  grid-template-columns: 1.4fr 1fr;
  gap: var(--space-10);
  align-items: center;
}
@media (max-width: 800px) { .cta-band { grid-template-columns: 1fr; } }
.cta-band h2 {
  font-size: var(--text-2xl);
  font-weight: 500;
  letter-spacing: -0.025em;
  line-height: 1.05;
}
.cta-band p { color: var(--color-text-muted); margin-top: var(--space-3); max-width: 50ch; }
.cta-actions { display: flex; flex-wrap: wrap; gap: var(--space-3); justify-content: flex-start; }
@media (min-width: 800px) { .cta-actions { justify-content: flex-end; } }

/* ---------- Page intro (interior pages) ---------- */
.page-intro {
  padding-block: clamp(var(--space-16), 8vw, var(--space-24)) clamp(var(--space-8), 4vw, var(--space-16));
  border-bottom: 1px solid var(--color-divider);
  background: var(--grad-hero);
}
.page-intro h1 {
  font-size: var(--text-2xl);
  font-weight: 500;
  letter-spacing: -0.03em;
  max-width: 22ch;
}
.page-intro p {
  margin-top: var(--space-5);
  font-size: var(--text-lg);
  color: var(--color-text-muted);
  max-width: 56ch;
  line-height: 1.55;
}